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| 1: Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common inherited disorders in humans |
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2: ADPKD is a multisystemic and progressive disorder characterized by formation and enlargement of renal cysts in the kidney and other organs (eg, liver, pancreas, spleen). Clinical features usually begin in the third to fourth decade of life, but cysts may be detectable in childhood and in utero.
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3: Ultrasound - This is the most useful imaging technique for diagnosing ADPKD, and it can detect cysts from 1-1.5 cm.
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4: Cerebral aneurysms are the major vascular abnormality and most serious complication of ADPKD; they occur in 4-10% of patients with ADPKD. |
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